The Sinergia project " Boron Nitride Nanomesh for Guided Self-Assembly of Molecular Arrays in Solutions " is funded by the Swiss National Science Foundation. It consists in a consortium of one Belgian and three Swiss research groups. The nanostructured material based on a single layer of hexagonal boron nitride (h-BN) on a Rh(111) surface shall be further investigated. This single-layer template is also stable in various liquids and can be imaged by scanning tunneling microscopy in an electrolyte solution. The step into the liquid was not preconceived in the previous project and opens entirely new opportunity windows for templated molecular self-assembly. Not only do simple and cheap dip-coating or electrochemical processes become available for the large-scale production of well defined molecular layers, but the range of molecular species that can be organized on top of this template is no longer restricted by the stringent requirement of vacuum sublimation.